Engineering Diversity

Author Archive

Fabrication of Shape-conformable Batteries Based on 3D-printing Technology
Jennifer A. Lewis | Dec. 19, 2018

Flexible, wireless electronic devices are rapidly emerging and have reached the level of commercialization; nevertheless, most of battery shapes are limited to either spherical and/or rectangular structures, which results in inefficient space use. Professor Il-Doo Kim’s team from the Department of Materials Science at KAIST has successfully developed technology to significantly enhance the variability of battery design through collaboration research with Professor Jennifer A. Lewis and her team from the School of Engineering and Applied Sciences at Harvard University.

Most of the battery shapes today are optimized for coin cell and/or pouch cells. Since the battery as an energy storage device occupies most of the space in microelectronic devices with different designs, new technology to freely change the shape of the battery is required.

FDA approves device based on Vanderbilt invention to ID parathyroid during head and neck surgeries
Anita Mahadevan-Jansen | Dec. 17, 2018

Ten years after Professor of Biomedical Engineering Anita Mahadevan-Jansen discovered that parathyroid tissues glow under near-infrared light, the FDA has approved a device based on the technology for surgical use.

She and her team developed the technology at the Vanderbilt Biophotonics Center. The device called “PTeye” has been tested at Vanderbilt University Medical Center and Ohio State University Medical Center in an 81-patient clinical study, leading to regulatory approval. It enables real-time identification of parathyroid tissue during thyroid and parathyroid surgeries.

Researchers evaluate pMSCs sheets for engineered repair and regeneration of heart tissue
Joyce Wong | Dec. 7, 2018

The placenta offers an abundant source of placenta-derived mesenchymal stem cells (pMSCs), which a new study has shown can readily form cell sheets that could be implanted in children with congenital heart defects and offer benefits for heart repair and regeneration compared to commonly used synthetic material-based scaffolds. Congenital heart disease is the leading cause of birth-defect-related illness and death. The placenta can be readily collected at birth and the cells harvested for pediatric reparative procedures, as described in the study published in Tissue Engineering, Part A, peer-reviewed journal from Mary Ann Liebert, Inc., publishers. Click here to read the full-text article free on the Tissue Engineering website through January 7, 2019.

Sitaram Emani, MD, Breanna Piekarski, RN, and Sirisha Emani, Children’s Hospital, Boston, MA and Erin Roberts, Kevin Huang, and Joyce Wong, PhD, Boston University, MA are the coauthors of the article entitled “Evaluation of Placental Mesenchymal Stem Cell Sheets for Myocardial Repair and Regeneration .” In the study, the researchers evaluated MSCs independent of their source, demonstrated their ability to form cell sheets, and described other beneficial effects related to paracrine section and cell-cell interactions at the site of MSC implantation. The ability of MSCs to secrete factors to induce cardioprotection, stimulate angiogenesis, and promote migration, proliferation and differentiation of local cardiac stem cells can all affect tissue repair.

JenaValve Technology Receives FDA Approval for Expanded IDE Enrollment in the Treatment of Patients with Severe Aortic Stenosis and Severe Aortic Regurgitation
Victoria Carr-Brendel | Dec. 3, 2018

JenaValve Technology, Inc., a developer and manufacturer of differentiated transcatheter aortic valve replacement (TAVR) systems, today announced U.S. Food and Drug Administration (FDA) approval of expansion of its Investigational Device Exemption (IDE) feasibility studies for the JenaValve Pericardial TAVR System with the Everdur™ transcatheter heart valve (THV) and Coronatix TM Transfemoral Delivery Catheter. The approval expands eligible patient enrollment from 20 patients at extreme or high surgical risk (10 aortic stenosis [AS], 10 aortic regurgitation [AR]) to 80 patients at extreme or high surgical risk (40 AS, 40 AR) at up to 10 U.S. sites.

The prospective IDE studies are part of a larger, ongoing CE Mark clinical program investigating the JenaValve Pericardial TAVR System for the same indications at centers of excellence in Europe and New Zealand.

With these nanoparticles, a simple urine test could diagnose bacterial pneumonia
Sangeeta Bhatia | Nov. 29, 2018

Pneumonia, a respiratory disease that kills about 50,000 people in the United States every year, can be caused by many different microbes, including bacteria and viruses. Rapid detection of pneumonia is critical for effective treatment, especially in hospital-acquired cases which are often more severe. However, current diagnostic approaches often take several days to return definitive results, making it harder for doctors to prescribe the right treatment.

MIT researchers have now developed a nanoparticle-based technology that could be used to improve the speed of diagnosis. This type of sensor could also be used to monitor whether antibiotic therapy has successfully treated the infection, says Sangeeta Bhatia, the John and Dorothy Wilson Professor of Health Sciences and Technology and Electrical Engineering and Computer Science and the senior author of the study.

Potential arthritis treatment prevents cartilage breakdown
Paula Hammond | Nov. 28, 2018

Osteoarthritis, a disease that causes severe joint pain, affects more than 20 million people in the United States. Some drug treatments can help alleviate the pain, but there are no treatments that can reverse or slow the cartilage breakdown associated with the disease.

In an advance that could improve the treatment options available for osteoarthritis, MIT engineers have designed a new material that can administer drugs directly to the cartilage. The material can penetrate deep into the cartilage, delivering drugs that could potentially heal damaged tissue.

Guiseppi-Elie named associate dean of EnMed
Anthony Guiseppi-Elie | Nov. 27, 2018

Dr. Anthony Guiseppi-Elie has been named associate dean of Engineering Medicine (EnMed) at Texas A&M University. He is currently a TEES Research Professor and professor in the Department of Biomedical Engineering with a courtesy appointment in the Department of Electrical and Computer Engineering.

EnMed is Texas A&M University’s innovative engineering medicine school option at Houston Methodist Hospital, developed to educate a new kind of physician to create transformational technology for health care.

Quantitative Analysis Improves Breast Screening: Research Highlights from RSNA
Elizabeth Burnside | Nov. 27, 2018

Quantitative analysis improves breast cancer screening, according to four abstracts at the 104th Annual Radiological Society of North America (RSNA) meeting, November 25–30, 2018. The investigators all used Volpara Solutions’ breast imaging analysis tools, including assessment of volumetric density and compression pressure, in their research.

In the study “Using Quantitative Breast Density Analysis to Predict Interval Cancers and Node Positive Cancers in Pursuit of Improved Screening Protocols,” (SSE01-03, Monday, November 26, 3:20–3:30 PM, Room: E451B), Elizabeth Burnside, MD, and colleagues investigated whether quantitative breast density can predict interval cancers and node-positive, screen-detected cancers in order to serve as a biomarker to consider more aggressive screening to improve early detection. The study involved 599 cases of screen-detected cancers and interval cancers and 605 controls from the UK NHS Breast Screening Programme. For each case, breast density was assessed by a radiologist using a visual analog scale (VAS) and BI-RADS 5th Edition density categories and using fully automated Volpara®Density™ software to calculate fibroglandular volume (FGV) and Volpara Density Grade (VDG®).

Martine LaBerge honored as Fellow by the Biomedical Engineering Society
Martine LaBerge | Nov. 1, 2018

Martine LaBerge of Clemson University is one of the newest Fellows in the Biomedical Engineering Society, an honor recognizing her for exceptional achievements and experience in biomedical engineering.

LaBerge is chair of the Department of Bioengineering at Clemson and executive director of the Clemson University Biomedical Engineering Innovation Campus, or CUBEInC, in Greenville.

Guillermo Ameer Receives Key to Panama City
Guillermo Ameer | Oct. 31, 2018

Northwestern Engineering’s Guillermo Ameer, a pioneer in the field of regenerative engineering, was presented the Key to Panama City, Panama, by Vice Mayor Raisa Banfield last week. The event was covered by Telemetro, a national Spanish-language television network based in Panama City.

Ameer, the Daniel Hale Williams Professor of Biomedical Engineering with the McCormick School of Engineering, was in his hometown to attend at APANAC 2018, the XVIII Congreso Nacional de Ciencia y Tecnologia, the nation’s premier science conference. He also serves as a professor of surgery at Northwestern University’s Feinberg School of Medicine, and he is the director of the Center for Advanced Regenerative Engineering (CARE).

Reinhart-King receives the inaugural BMES Mid-Career Award
Cynthia Reinhart-King | Oct. 25, 2018

Cynthia A. Reinhart-King, a nationally recognized cellular bioengineer, is the inaugural recipient of the Biomedical Engineering Society’s Mid-Career Award. Reinhart-King delivered the award lecture Saturday, Oct. 20, at the BMES 2018 Annual Meeting in Atlanta.

Reinhart-King received the 2010 Rita Schaffer Young Investigator Award and she is the only person to have received two of three major awards from the BMES.

Cryptographic protocol enables greater collaboration in drug discovery
Bonnie Berger | Oct. 18, 2018

MIT researchers have developed a cryptographic system that could help neural networks identify promising drug candidates in massive pharmacological datasets, while keeping the data private. Secure computation done at such a massive scale could enable broad pooling of sensitive pharmacological data for predictive drug discovery.

Datasets of drug-target interactions (DTI), which show whether candidate compounds act on target proteins, are critical in helping researchers develop new medications. Models can be trained to crunch datasets of known DTIs and then, using that information, find novel drug candidates.

Gilda Barabino, Ph.D.

Gilda A. Barabino is Dean and Berg Professor at The Grove School of Engineering at The City College of New York (CCNY). She has appointments in Biomedical Engineering, Chemical Engineering and the Sophie Davis School of Biomedical Education / CUNY School of Medicine. Prior to joining CCNY, she served as Associate Chair for Graduate Studies and Professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory. At Georgia Tech she also served as the inaugural Vice Provost for Academic Diversity. Prior to her appointments at Georgia Tech and Emory, she rose to the rank of Full Professor of Chemical Engineering and served as Vice Provost for Undergraduate Education at Northeastern University. She is a noted investigator in the areas of sickle cell disease, cellular and tissue engineering, and race/ethnicity and gender in science and engineering. She consults nationally and internationally on STEM education and research, diversity in higher education, policy, workforce development and faculty development.

Dr. Barabino received her B.S. degree in Chemistry from Xavier University of Louisiana and her Ph.D. in Chemical Engineering from Rice University. She is a Fellow of the American Association for the Advancement of Science, the American Institute for Medical and Biological Engineering (AIMBE) and the Biomedical Engineering Society (BMES). She was the Sigma Xi Distinguished Lecturer for 2012-2014. She has an extensive record of leadership and service in the chemical and biomedical engineering communities. She is the Immediate Past-President of BMES and is the President-Elect of AIMBE. Dr. Barabino has over a decade of experience in leading NSF initiatives for women and minority faculty and is the founder and Executive Director of the National Institute for Faculty Equity.

Education

  • PhD in Chemical Engineering, Rice University, Houston, TX
  • BS in Chemistry, Xavier University, New Orleans, LA

Research Interests

Barabino Laboratory on Vascular and Orthopedic Tissue Engineering Research is primarily focused on cellular and tissue responses to fluid mechanical forces in the context of vascular disease and orthopedic tissue engineering. We concentrate on the characterization and quantification of mechanical and biochemical cues that influence tissue growth and disease progression. Our interdisciplinary work incorporates biology, materials science and engineering toward novel therapeutic strategies to improve the health of individuals suffering with sickle cell disease and those suffering with diseases associated with damaged cartilage and bone. To that end, we employ innovative engineering technologies to create models that recapitulate the environment within the body in order to better understand the pathophysiology of disease and the most appropriate strategies for treatment. We also employ complementary animal models to bridge translation of our findings to human clinical practice.

Sickle Cell Disease (SCD)

SCD is a genetic disorder affecting 70,000 Americans and millions globally that induces chronic inflammation and vascular dysfunction and causes multiple organ damage as a result. The pathophysiology of SCD is quite complex and involves altered interactions between blood cells and endothelial cells lining the vessel walls, altered mechanical properties of blood, blood cells and blood vessels and altered tissue properties in affected organs. We apply innovative engineering approaches and technologies to better understand conditions that contribute to vaso-occlusion, a hallmark of the disease, and the relationship between inflammation, vascular remodeling and vascular biomechanical abnormalities. Results from these studies will enable the development of new therapies and provide clinicians with therapeutic opportunities for improved management of individuals with SCD.

Cartilage Tissue Engineering

Articular cartilage injury is a major cause of decreased mobility and pain and can lead to osteoarthritis, a debilitating disease characterized by progressive erosion of cartilage tissues. Once injured or damaged due to disease, cartilage has limited ability for regeneration and self-repair due to its avascular nature. Tissue engineering approaches combining cells, bioactive molecules and biodegradable scaffolds in defined environments that support the regeneration of functional cartilage tissues hold promise. Bioreactors are used to provide defined environments and we have developed and employed novel bioreactor systems that impart fluid flow-induced shear forces to better understand how environmental factors regulate tissue growth toward the development of optimally designed and clinically relevant engineered tissues.

Connecting the dots of Alzheimer’s disease
Ellen Kuhl | Oct. 15, 2018

Some people may follow a football team, others may follow their favorite television streaming series. For Ellen Kuhl, PhD, a professor of mechanical engineering at Stanford, her passion lies in following proteins. In a recent Stanford news article, Kuhl explains how her team developed a computer simulation to track the spread of defective proteins in the brain. These proteins contribute to the progression of neurodegenerative diseases such as Alzheimer’s, Parkinson’s, ALS and Lou Gehrig’s disease.

Eyeing NASH, Glympse Raises $22M to Test Disease Detection Nanotech
Sangeeta Bhatia | Oct. 9, 2018

Glympse Bio has developed sensor technology that it says can give clinicians an early look at a developing disease. As Glympse prepares to test its disease detection approach in a serious liver disorder, the startup has raised $22 million in Series A financing.

LS Polaris Innovation Fund and Arch Venture Partners co-led the investment in Cambridge, MA-based Glympse.

The startup has developed bioengineered nanoparticles that circulate through the body, detect disease, and report their findings through a signal read by testing the patient’s urine. The company, which spun out from the laboratory of MIT professor Sangeeta Bhatia, says its “activity sensors” can test for multiple indicators of disease, such as cancer, fibrosis, immune disorders, and infectious disease. Glympse also says its technology can monitor how a patient’s disease is responding to a drug.

To improve anesthesia, focus on neuroscience and nociception, experts urge
Emery Brown | Oct. 4, 2018

People sometimes mistakenly think of general anesthesia as just a really deep sleep, but in fact, anesthesia is really four brain states — unconsciousness, amnesia, immobility, and suppression of the body’s damage sensing response, or “nociception.” In a new paper in Anesthesia and Analgesia, MIT neuroscientist and statistician Emery N. Brown and his colleagues argue that by putting nociception at the top of the priority list and taking a principled neuroscientific approach to choosing which drugs to administer, anesthesiologists can use far less medication overall, producing substantial benefits for patients.

“We’ve come up with strategies that allow us to dose the same drugs that are generally used but in different proportions that allow us to achieve an anesthetic state that is much more desirable,” says Brown, the Edward Hood Taplin Professor of Computational Neuroscience and Health Sciences and Technology in the Picower Institute for Learning and Memory at MIT and a practicing anesthesiologist at Massachusetts General Hospital.

The Engineer – Inventing a toolkit for newborns in need
Rebecca Richards-Kortum | Oct. 1, 2018

Two years ago on Halloween, Rebecca Richards-Kortum, Ph.D., a professor of bioengineering at Rice University, walked into her lab and stopped abruptly. Staring back at her was a crowd of familiar characters.

Her students, who wear costumes for the holiday every year, had conspired to go as different versions of their mentor. There was the mother-of-six Rebecca, the saving-dying-babies-in-Africa Rebecca, the marathon-runner Rebecca, even the Albert-Einstein Rebecca—a nod to the $625,000 fellowship Richards-Kortum received from the MacArthur Foundation. Commonly known as a “genius grant,” the stipend is paid out over five years to support visionaries in their creative pursuits for the benefit of humanity…

Guillermo Ameer, ScD

Dr. Guillermo Ameer, Daniel Hale Williams Professor of Biomedical Engineering and Surgery at Northwestern University, is creating a set of high-tech tools to manage diverse medical conditions. Dr. Ameer directs the Center for Advanced Regenerative Engineering (CARE) which integrates and supports research, technology development, and clinical expertise to improve the outcome of tissue and organ repair and regeneration for adult and pediatric patients. Dr. Ameer’s lab develops biomaterials and nanotechnology for regenerative engineering, tissue engineering, medical devices, drug delivery, and cell delivery applications. In the lab, projects driving the creation and engineering of novel biomaterials to target and treat vascular, endocrine, and bone pathophysiologies are on deck. Dr. Ameer has co-authored over 200 peer-reviewed journal publications and conference abstracts, several book chapters, and multiple patents issued and pending (>35). He has founded 3 companies: ProSorp Biotech, VesselTek Biomedical and Citrics Biomedical.

Not One More Generation: Women in Science Take on Sexual Harassment
ASBMB Today

I was driven out of science by a harasser in the 1980s.”

Coming from a woman who has since helped to found a scientific society, served as director of the Genetics Society of America and presented her research on sexual harassment to a 2018 National Academies panel, it is a surprising statement. But Sherry Marts left academia after finishing her Ph.D. at Duke and never went back.

2018 has been a banner year for confronting sexual harassment in science. The National Academies of Sciences, Engineering and Medicine published a report on the high prevalence of harassment of women in science, and the National Institutes of Health and National Science Foundation are updating their sexual harassment policies. It appears that science might be catching up with the #MeToo movement, which has raised awareness of workplace sexual harassment. However, critics say that large institutions are moving too incrementally and could do much more.

Treena Arinzeh, PhD

Treena Livingston Arinzeh, Professor of Biomedical Engineering at the New Jersey Institute of Technology, has earned national recognition for her commitment to making adult stem cell therapy a future reality. Her research interests are in stem cell tissue engineering and applied biomaterials, with a focus in the development of functional biomaterials that can accelerate repair utilizing stem cells and other cell types. She develops biomaterial strategies for the repair of bone, cartilage and other related musculoskeletal tissues. Her research interests also include nerve tissue regeneration, specifically spinal cord. In fall 2004, President Bush awarded Arinzeh the Presidential Early Career Award for Scientists and Engineers, the highest national honor that a young researcher can receive. In 2003, the National Science Foundation also gave Arinzeh its highest honor–a Faculty Early Career Development award that included a $400,000 research grant. Arinzeh’s most cited work to date, in a paper in the Journal of Bone and Joint Surgery, demonstrated that adult stem cells taken from one person could be implanted in another without being rejected. It was among the most significant findings in stem cell research in the past few years.

Gilda Barabino, PhD

Gilda Barabino would become the first African American student admitted to Rice University to pursue a Ph.D. in chemical engineering – a daunting and pioneering solo status, one of many firsts for Barabino, that didn’t stop her from following her dream of becoming a biomedical engineer. Gilda Barabino is the Dean of the Grove School of Engineering at The City College of New York (CCNY). She is a noted investigator in the areas of sickle cell disease, cellular and tissue engineering, and race/ethnicity and gender in science and engineering. She consults nationally and internationally on STEM education and research, diversity in higher education, policy, workforce development and faculty development. She is a Past-President of BMES and AIMBE. Dr. Barabino has over a decade of experience in leading NSF initiatives for women and minority faculty and is the founder and Executive Director of the National Institute for Faculty Equity.

Decoding the Brain
Karen Moxon | Sep. 7, 2018

In the last decade, researchers in academia and the technology sector have been racing to unlock the potential of artificial intelligence. In parallel with federally-funded efforts from the National Institutes of Health and the National Science Foundation, heavy-hitters such as Microsoft, Facebook and Google are deeply invested in artificial intelligence.

As part of the BRAIN Initiative, many University of California, Davis investigators across campus are studying the nervous system and developing new technologies to investigate brain function.

Reverse-engineering the brain is a central tenet to reproducing human intelligence. However, experts say, most efforts to design artificial brains haven’t involved giving much attention to real ones. By understanding how our brains work, we can leverage artificial intelligence to test new drug therapies for brain disorders, and one day even circumvent neurological disorders such as Alzheimer’s disease or Parkinson’s disease…

Barbara Boyan, Ph.D.

Barbara D. Boyan, Ph.D., dean of VCU’s School of Engineering, is an acclaimed researcher and entrepreneur. Her laboratory focuses on research related to all aspects of bone and cartilage biology, and she is recognized internationally by peers as an expert in musculoskeletal tissue engineering, regenerative medicine and cell and tissue interactions with biomaterials. Dean Boyan is inventor on 22 U.S. and multiple international patents. Her inventions focus on innovative ways to treat musculoskeletal defects by harnessing the body’s own regenerative potential. Notable examples include a micro-nanoscale surface technology for dental and spine implants, as well as a biodegradable implant for regenerating bone and cartilage.

Dean Boyan is committed to advancing scholarship in science and engineering. She has been an invited lecturer in over 15 countries and, on average, participates in the scientific programs of 20 conferences each year. Dean Boyan is author of more than 460 peer-reviewed papers, reviews and book chapters. She has mentored over 30 doctoral and 50 master’s students. Her research, leadership and mentorship have earned her honors and appointments from numerous organizations, including:

  • Fellow – American Institute for Medical and Biological Engineering (AIMBE)
  • Fellow – American Association for the Advancement of Science (AAAS)
  • Fellow – National Academy of Inventors (NAI)
  • Member – National Academy of Engineering (NAE)
  • Fellow – World Congress of Biomaterials
  • Founding Director – Atlanta Pediatric Device Consortium
  • Co-Director – Atlantic Pediatric Device Consortium
  • National Materials Advisory Board Member – National Research Council of the National Academies
  • Appointment – National Materials Advisory Board
  • Past Chair – Orthopaedic Device Panel, U.S. Food and Drug Administration
  • Past President – American Association of Dental Research
  • National Research Council
 Birnberg Award–Columbia University School of Dentistry

Dean Boyan is strongly committed to entrepreneurship and the translation of discoveries to industrial applications. She is the co-founder of four companies:

  • SpherIngenics, Inc., (cell-based therapies) as Director and Chief Scientific Officer
  • Orthonics, Inc., (medical devices) as Chief Scientific Officer
  • OsteoBiologics, Inc., (tissue engineered medical products) as Chairman and CEO, Board of Directors
  • Biomedical Development Corporation, (innovative medical technologies) Chief Scientific Officer

She also serves on the board of directors for five other companies:

  • Carticept Medical, Inc., (innovative injection devices) Independent Director, Board of Directors, and Chief Scientific Officer
  • Cartiva, Inc. (Cartilage repair technologies) Independent Director, Board of Directors, and Chief Scientific Officer
  • IsoTis, Inc., (Bone graft material) Independent Director, Board of Directors, and Chief Scientific Officer
  • IsoTis SA, (Bone graft material) Independent Director, Board of Directors
  • ArthroCare, Inc., (Medical devices) Independent Director, Board of Directors

Previously the associate dean for research and innovation at the College of Engineering at the Georgia Institute of Technology, Dean Boyan has been involved in research and education since 1974. She received her B.A., M.A., and Ph.D. in biology at Rice University, and is the recipient of many scholarly and national awards. She is an active proponent of collaboration and interdisciplinary studies within the university.

Rena Bizios, Ph.D.

Professor Rena Bizios, a chemical/biomedical engineer by training, is the Lutcher Brown Chair Professor in the Department of Biomedical Engineering at the University of Texas at San Antonio, San Antonio, Texas. During her career in academia, Professor Bizios has taught various undergraduate and graduate fundamental engineering and biomedical engineering courses as well as developed new courses for biomedical engineering curricula. She has mentored many undergraduate and graduate students, post-doctoral fellows, and junior faculty. Her research interests include cellular and tissue engineering, tissue regeneration, biomaterials (including nanostructured ones) and biocompatibility. She has co-authored a textbook (entitled An Introduction to Tissue-Biomaterial Interactions), co-edited a book (Biological Interactions on Material Surfaces: Understanding and Controlling Protein, Cell and Tissue Responses), authored/co-authored scientific publications and book chapters, and is co-inventor of several patents/disclosures. She has given numerous presentations at scientific conferences and invited seminars/lectures in academic institutions and industry. She has also organized and/or co-chaired numerous symposia and sessions at regional/national/international conferences. Professor Bizios is a member and has been an active participant (including elected officer positions) in several professional societies. She is member of the editorial board of the Journal of Biomedical Materials Research, Part A and Part B, Technology, Journal of Nano Research, and Regenerative Engineering and Translational Medicine; she has participated in various national-level review committees, and has served on numerous Departmental, School/College of Engineering and Institute/University committees.

Professor Bizios’ contributions to education and her research accomplishments have been recognized by the: Rensselaer Alumni Association Teaching Award (1997); Clemson Award for Outstanding Contributions to the Literature by the Society for Biomaterials, (1998); Distinguished Scientist Award by the Houston Society for Engineering in Medicine and Biology (2009); Women’s Initiatives Mentorship Excellence Award by The American Institute of Chemical Engineers (2010); Founders Award by the Society for Biomaterials (2014); Theo C. Pilkington Outstanding Educator Award by the Biomedical Engineering Division, American Society for Engineering Education (2014); Amber Award, The UTSA Ambassadors, The University of Texas at San Antonio (2014); and by her election as Charter Member of the Academy of Distinguished Researchers, The University of Texas at San Antonio (2015). Professor Bizios is Fellow of the American Institute for Medical and Biological Engineering (AIMBE), International Union of the Societies for Biomaterials Sciences and Engineering, Biomedical Engineering Society (BMES), American Institute of Chemical Engineers (AIChE), and of the American Association for the Advancement of Science (AAAS). She is also member of the National Academy of Medicine (NAM) and of the Academy of Medicine, Engineering and Science of Texas (TAMEST).

Linda Lucas, Ph.D.

Dr. Linda C. Lucas became provost of University of Alabama at Birmingham in April 2012 after serving in the interim role since May 2011. She served as dean of the School of Engineering from 2000 to 2011. Lucas joined the UAB faculty in 1982 as an assistant professor and was named department chair of biomedical engineering in 1995. She is a senior scientist in the Center for BioMatrix Engineering and Regenerative Medicine and the Center for Metabolic Bone Diseases. She also holds joint appointments in the Department of Materials Science and Engineering and several departments within the School of Dentistry.

Lucas holds a Bachelor of Science in mathematics and chemistry from the University of Alabama; she also earned bachelor’s and master’s degrees in engineering, a Master of Science in mathematics, a Master of Arts in education, and a Ph.D. in biomedical engineering from UAB.  She has focused her academic career on the development of biomaterials for orthopaedic and dental implants.

Dr. Lucas was on the inaugural Council of the National Institute of Biomedical Imaging and Bioengineering and is the first female past-president of three international professional organizations: the American Institute for Medical and Biological Engineering, the Biomedical Engineering Society, and the Society for Biomaterials. In 1998 she was inducted as a Fellow in the American Institute for Medical and Biological Engineers, and in 2000 she was inducted as an International Fellow in the Society for Biomaterials. Dr. Lucas and her students have presented their work in over 100 publications and made more than 250 presentations at scientific meetings.

Katherine Ferrara, Ph.D.

Dr. Katherine Ferrara was recruited to the Department of Radiology at Stanford University in 2018. Prior, Professor Ferrera spent years building and shaping the Biomedical Engineering Department at the University of California, Davis into a highly successful program.

Most recently, Professor Ferrara became IEEE Distinguished Lecturer in 2017 and received the inaugural Leadership in Molecular Imaging Award in 2018.

In 2011, Professor Katherine Ferrara was presented with an Outstanding Mentor Award from the Consortium for Women and Research at UC Davis. These awards honor faculty members who have engaged in sustained and successful mentoring of women at the university; Ferrara was nominated by students and peers, many of whom wrote lengthy and quite moving letters of support.

Kathy Ferrara was elected to the National Academy of Engineering for her contributions to the theory and applications of biomedical ultrasound technology.

This accolade was merely one example of Ferrara’s ability to juggle ambitious responsibilities in teaching, research and administration: the latter, most impressively, when she was recruited to found the UC Davis Department of Biomedical Engineering, and then served a five-year term as the department’s first chair, from 2000 to ’05. When she stepped down, the fledgling department already ranked 23rd in the nation, with extramural expenditures that were among the country’s largest.

This was Ferrara’s second stint on the Davis campus. After obtaining undergraduate and master’s degrees in electrical engineering from Sacramento State University, she earned a doctorate in the same field from UC Davis in 1989. She then held appointments at the University of Virginia and New York’s Cornell Medical College, while maintaining an associate professorship at Sacramento State. Upon her return to UC Davis in 1998, her efforts in the nascent Department of Biological Engineering included planning for her department’s space in what eventually would become the campus’ Genome and Biomedical Sciences Facility.

During the subsequent decade, her research focused on cancer diagnosis and the paradigm-shifting concept of “image-guided drug delivery,” a form of individualized therapy wherein imaging methods — ultrasound, PET, MRI and CT — are used to guide and monitor the localized, targeted delivery of therapeutics to (for example) a cancer tumor. Ferrara’s lab also is developing molecularly targeted drug delivery vehicles.

Ferrara is a fellow of the Acoustical Society of America, the American Institute of Medical and Biological Engineering, and the Biomedical Engineering Society. She was chosen to deliver the 2011 Chandran Lecture at Duke University’s Pratt School of Engineering; the lecture series focuses on advances in brain tumor imaging. In March 2012, she gave the Adamczyk Lecture at Case Western Reserve University; this lecture series showcases the use of cutting-edge technology in the development of noninvasive diagnostics and novel therapies, particularly in the context of cancer treatments. In both cases, Ferrara’s selection reflects the degree to which she has been recognized as a nationally respected scientist whose work will have a major impact on medical technology, now and in the future.

Banu Onaral, Ph.D.

Dr. Onaral is H. H. Sun Professor of Biomedical Engineering and Electrical Engineering at Drexel University, Philadelphia, PA. She holds a Ph.D. in Biomedical Engineering from the University of Pennsylvania and BSEE and MSEE in Electrical Engineering from Bogazici University, Istanbul, Turkey. Dr. Onaral joined the faculty of the Department of Electrical and Computer Engineering and the Biomedical Engineering and Science Institute in 1981. Since 1997, she has served as the founding Director of the School of Biomedical Engineering Science and Health Systems. 

Her academic focus is centered on information engineering with special emphasis on complex systems and biomedical signal processing in ultrasound and optics. She has led major research and development projects sponsored by the National Science Foundation (NSF), National Institutes of Health (NIH), Office of Naval Research (ONR), DARPA and Department of Homeland Security (DHS). She has supervised a large number of graduate students to degree completion and has an extensive publication record in biomedical signals and systems. She is the recipient of a number of faculty excellence awards, including the Lindback Distinguished Teaching Award of Drexel University, the EDUCOM Best educational Software award, and the NSF Faculty Achievement Award. 

Dr. Onaral’s translational research efforts for rapid commercialization of biomedical technologies developed at Drexel and its partner institutions have resulted in the creation of the Translational Research in Biomedical Technologies program. This initiative brings together academic technology developers with entrepreneurs, regional economic development agencies, as well as local legal, business, and investment communities. Under her leadership, the Coulter Translational Research Partnership Award recognized the program following a highly competitive selection process among 63 institutions in North America. At the end of an initial five-year term, universities successful in institutionalizing translational research will receive an endowment to ensure the perpetuity of the program.

Her professional responsibilities have included service on the Editorial Board of journals and the CRC Biomedical Engineering Handbook as Section Editor for Biomedical Signal Analysis. She served as President of the IEEE Engineering in Medicine and Biology Society (EMBS), the largest member-based biomedical engineering society in the world. She organized and chaired the 1990 Annual International Conference of the EMBS and Co-Chaired the 2004 Annual Conference of the Biomedical Engineering Society (BMES). She is a Fellow of the IEEE Engineering in Medicine and Biology Society, the American Association for the Advancement of Science (AAAS), and a Founding Fellow of the American Institute for Medical and Biological Engineering (AIMBE). She served on the inaugural Board of the AIMBE as publications chair and as Chair of the Academic Council. She currently serves as the President of the Turkish American Scientists and Scholars Association (TASSA).

Janice Jenkins, Ph.D.

During her 22-year career at the University of Michigan, Janice Jenkins became known for her mentorship and dedication to the development of the next generation of research engineers — and for the fact that she was the first woman faculty member hired in the Electrical and Computer Engineering Department.

“The most unusual part of my academic career,” Jenkins said, “is the fact that I raised five kids and started college when my oldest started college. I was 37. I got my PhD at the age of 46 and was appointed an assistant professor at Michigan at the age of 48. I wasn’t as worried about being discriminated against for being female, as I was worried about age discrimination! I didn’t tell anyone how old I was. I won the NSF Presidential Young Investigator award when I was 52. Probably (without doubt) the oldest Young Investigator ever. I was a grandmother!”

At the time of her retirement in 2002, Jenkins still had an active NSF grant at UM and traveled back to Michigan regularly, supervising the research of two graduate and three undergraduate students. “I haven’t stopped my active professional life,” she said. “I also have a major role in an NIH/SBIR grant and am directing clinical studies at Loyola University Medical Center.”

Professor Jenkins received her BS, MS, and PhD degrees from the University of Illinois at Chicago in 1974, 1976, and 1978, respectively. She was an assistant professor of electrical engineering and computer science, and of medicine, at Northwestern University from 1979-1980. In 1980, she joined the UM faculty as an assistant professor of electrical and computer engineering and was promoted to professor of electrical engineering and computer science, and of biomedical engineering, in 1992.

At UM, Jenkins made important contributions to automated arrhythmia analysis using advanced signal processing and computer techniques. She was director of the medical computing research laboratory (1981-2002), and of the digital design laboratory (1983-1998), an instructional laboratory on the design of microprocessor-based systems that she initiated and taught.

In 1991, Jenkins received the UM Sarah Goddard Power Award for her outstanding professional achievements and contributions to the education of women, and the NSF Faculty Award for Women in Science and Engineering. Jenkins is a Fellow of the Institute of Electrical and Electronics Engineers, the American Institute for Medical and Biological Engineering, and the American College of Cardiology. She has four patents, and another pending. She has supported, mentored, and graduated 20 PhD students and eight MS thesis students.

Upon her retirement from active faculty status in December 2002, the UM Regents named Janice Jenkins Professor Emerita of Electrical Engineering and Computer Science.

Christina Enroth-Cugell, Ph.D.

Christina Alma Elisabeth Enroth-Cugell, emeritus professor of biomedical engineering and neurobiology, passed away June 15, 2016 at age 96. She was as a renowned vision scientist, distinguished researcher, and compassionate colleague.

Arriving at Northwestern in 1955, Enroth-Cugell worked as a research fellow and instructor in the University’s Department of Ophthalmology before transitioning to the role of faculty in the Department of Physiology. In 1968, she began a joint appointment between the Weinberg College of Arts and Sciences and the McCormick School of Engineering and Applied Science, where she was one of the first female faculty members to teach engineering at Northwestern. She was an early faculty member of what became McCormick’s Department of Biomedical Engineering and Weinberg’s Department of Neurobiology and served as chair of the Department of Neurobiology from 1984-1986.

A celebrated researcher, Enroth-Cugell made several contributions to the areas of visual adaptation and the spatial and temporal aspects of receptive fields and was at the center of the study of vision at Northwestern. Her lab, where she continued to play an active role well after her retirement in 1990, was a vital hub for producing many of today’s vision scientists.

Enroth-Cugell’s research concentrated on the physiology of the mammalian retina, a passion that dated back to her time as a student at the Karolinska Institute in Stockholm, where she earned her PhD under Nobel Prize-winning scientist Ragnar Granit. Her particular interest in feline retinal ganglion cells led to her seminal research published in 1966 with collaborator John G. Robson. The study, which has been cited nearly 2,000 times, was one of the first to use systems analysis methods in vision, and it launched a field of study on parallel pathways in the visual system.

In 1983, Enroth-Cugell received the prestigious Jonas Stein Friedenwald Award from the Association for Research in Vision and Ophthalmology for her groundbreaking research and contributions to the study of visual physiology.

Enroth-Cugell was recognized with several notable accolades throughout her career. She received the inaugural Ludwig von Sallmann Prize at the International Congress of Eye Research meeting in 1982, as well as an honorary degree from the University of Helsinki. She also served as a member of the National Institute of Health’s National Advisory Eye Council and was named fellow of the American Academy of Arts and Sciences. In 1994, she was inducted into the American Institute for Medical and Biological Engineering’s College of Fellows for “distinguished contributions to basic visual science.”

Sangeeta Bhatia, MD, PhD

Sangeeta Bhatia is a cancer researcher, MIT professor and biotech entrepreneur who works to adapt technologies developed in the computer industry for medical innovation. Trained as both a physician and engineer, Sangeeta’s laboratory leverages ‘tiny technologies’ of miniaturization to yield inventions with new applications in tissue regeneration, stem cell differentiation, medical diagnostics, predictive toxicology, and drug delivery. She and her trainees have launched more than ten biotechnology companies to improve human health. Sangeeta has received many honors including the Lemelson-MIT Prize, known as the ‘Oscar for inventors,’ and the Heinz Medal for groundbreaking inventions and advocacy for women in STEM fields. She is a Howard Hughes Medical Institute Investigator and an elected member of the National Academy of Engineering, the National Academy of Science, the American Academy of Arts and Sciences, and the American Institute for Medical and Biological Engineering.

Deep Learning Attacks Joint Degeneration and Osteoarthritis: Musculoskeletal Imaging Research Published in ‘Radiology’
Sharmila Majumdar | Aug. 23, 2018

Deep learning has become a powerful tool in radiology in recent years. Researchers at the UC San Francisco Department of Radiology and Biomedical Imaging have started using deep learning methods to characterize joint degeneration and osteoarthritis, which will ultimately reduce the number of total joint replacements. In a recent paper published in Radiology (PubMed) they demonstrate that it is possible to automatically identify (segment) cartilage and meniscus tissue in the knee joint and extract measures of tissue structure such as volume and thickness, as well as tissue biochemistry, by a method know as MR relaxometry. Cartilage and meniscus morphological and biochemical changes are tissue-level symptoms of joint degeneration…

TRACKING PROGRESS

Recent studies on career choices of graduate students reveal a significant attrition from biomedical research careers at rates that disproportionally affect women and underrepresented individuals.

Black women receive fewer engineering degrees than almost any other group—just 1% in 2015, according to the American Society for Engineering Education—and that number has declined since 2011. Fewer than 5% of engineers are women of color; more attention and support could help to increase diversity in engineering.

Only 24 percent of engineering master’s students and 22 percent of doctoral candidates are women. In regard to the engineering workforce, 15 percent of workers are women and 1 in 10 workers are either black, Hispanic, or American Indian.

If the proportion of underrepresented students attaining PhDs in science were the same as those attaining bachelor’s degrees in the sciences, the number of Hispanic/Latino science doctorates would need to double, and the number of Black/African American science doctorates would need to triple.

Only 4 out of the 107 Historically Black Colleges and Universities (HBCUs) nationwide offers a Bachelor of Science (B.S.) in Bioengineering related fields.

MENTORING

Lorem ipsum dolor sit amet, amet lectus turpis, nulla sed tortor potenti, eu magnis, pellentesque dolor enim placerat egestas, duis bibendum est rutrum sed. Maecenas quis turpis, eros aliquam mauris ante. Mauris tempor elit cras purus tempus, ac vulputate lacus, consectetuer nulla dolor ante orci. Eu semper justo. Taciti molestie vivamus rutrum cras, interdum maecenas non risus bibendum, harum varius quis nec vel. Consequat lacus, aliquam tempor lacinia massa, aenean proin risus diam duis. Nulla fringilla nulla id et, orci lacus quis lorem wisi erat libero, penatibus posuere, ante blandit malesuada metus. Elit tempor eu nunc. Massa eget luctus elit netus nec rutrum, magna sed sed nec, non sed mi adipiscing hendrerit sollicitudin, inventore libero tempor et ante. Vestibulum odio rutrum auctor nec gravida nibh, tellus duis netus feugiat in justo nulla, egestas sollicitudin congue vestibulum tortor ac, eius quam et, nulla amet dictum dolor purus magna.

BUILDING EVIDENCE

Lorem ipsum dolor sit amet, amet lectus turpis, nulla sed tortor potenti, eu magnis, pellentesque dolor enim placerat egestas, duis bibendum est rutrum sed. Maecenas quis turpis, eros aliquam mauris ante. Mauris tempor elit cras purus tempus, ac vulputate lacus, consectetuer nulla dolor ante orci. Eu semper justo. Taciti molestie vivamus rutrum cras, interdum maecenas non risus bibendum, harum varius quis nec vel. Consequat lacus, aliquam tempor lacinia massa, aenean proin risus diam duis. Nulla fringilla nulla id et, orci lacus quis lorem wisi erat libero, penatibus posuere, ante blandit malesuada metus. Elit tempor eu nunc. Massa eget luctus elit netus nec rutrum, magna sed sed nec, non sed mi adipiscing hendrerit sollicitudin, inventore libero tempor et ante. Vestibulum odio rutrum auctor nec gravida nibh, tellus duis netus feugiat in justo nulla, egestas sollicitudin congue vestibulum tortor ac, eius quam et, nulla amet dictum dolor purus magna.

WHAT WORKS

Lorem ipsum dolor sit amet, amet lectus turpis, nulla sed tortor potenti, eu magnis, pellentesque dolor enim placerat egestas, duis bibendum est rutrum sed. Maecenas quis turpis, eros aliquam mauris ante. Mauris tempor elit cras purus tempus, ac vulputate lacus, consectetuer nulla dolor ante orci. Eu semper justo. Taciti molestie vivamus rutrum cras, interdum maecenas non risus bibendum, harum varius quis nec vel. Consequat lacus, aliquam tempor lacinia massa, aenean proin risus diam duis. Nulla fringilla nulla id et, orci lacus quis lorem wisi erat libero, penatibus posuere, ante blandit malesuada metus. Elit tempor eu nunc. Massa eget luctus elit netus nec rutrum, magna sed sed nec, non sed mi adipiscing hendrerit sollicitudin, inventore libero tempor et ante. Vestibulum odio rutrum auctor nec gravida nibh, tellus duis netus feugiat in justo nulla, egestas sollicitudin congue vestibulum tortor ac, eius quam et, nulla amet dictum dolor purus magna.

RESOURCES

Lorem ipsum dolor sit amet, amet lectus turpis, nulla sed tortor potenti, eu magnis, pellentesque dolor enim placerat egestas, duis bibendum est rutrum sed. Maecenas quis turpis, eros aliquam mauris ante. Mauris tempor elit cras purus tempus, ac vulputate lacus, consectetuer nulla dolor ante orci. Eu semper justo. Taciti molestie vivamus rutrum cras, interdum maecenas non risus bibendum, harum varius quis nec vel. Consequat lacus, aliquam tempor lacinia massa, aenean proin risus diam duis. Nulla fringilla nulla id et, orci lacus quis lorem wisi erat libero, penatibus posuere, ante blandit malesuada metus. Elit tempor eu nunc. Massa eget luctus elit netus nec rutrum, magna sed sed nec, non sed mi adipiscing hendrerit sollicitudin, inventore libero tempor et ante. Vestibulum odio rutrum auctor nec gravida nibh, tellus duis netus feugiat in justo nulla, egestas sollicitudin congue vestibulum tortor ac, eius quam et, nulla amet dictum dolor purus magna.